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Provigil has been approved by the United Stated Food and Drug Administration for the treatment of narcolepsy, shift work sleep disorder, and day time sleepiness that is caused by sleep apnea. In other markets it has only been approved for the treatment of narcolepsy. Additionally, Provigil has been approved to treat a wide variety of off lable indications. Provigil is often prescribed off label for the treatment of seasonal affect disorder which is also known as SAD, and may also be used as a doping agent for athletes. Provigil has been banned for athletes since 2004 by the World Anti-Doping Agency.

In addition to SAD, Provigil may also be used off label to treat the symptoms associated with Multiple sclerosis. Doctors will prescribe Provigil for the treatment of spastic cerebral palsy, Parkinson’s disease, opiod induced sleepiness, myotonic dystrophy, chronic fatigue syndrome, as well as fibromyalgia. The conditions that can be treated with Provigil seem to grow with each passing year.

Provigil is highly effective in treating a wide variety of diseases and conditions but it is not without its unintended side effects These side effects may include insomnia, agitation, anxiety, aggressiveness, confusion, tremor, sleep disturbance, nausea, and diarrhea. Patients who experience bothersome side effects should discuss their options with their doctor as they occur.